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PDE9A 抗体 (AA 426-533) (HRP)

PDE9A 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7155178
发货至: 中国
  • 抗原 See all PDE9A 抗体
    PDE9A (phosphodiesterase 9A (PDE9A))
    抗原表位
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 426-533
    适用
    • 23
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 4
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 18
    • 3
    • 2
    This PDE9A antibody is conjugated to HRP
    应用范围
    • 18
    • 12
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human High affinity cGMP-specific 3\',5\'-cyclic phosphodiesterase 9A protein (426-533AA)
    亚型
    IgG
    Top Product
    Discover our top product PDE9A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PDE9A (phosphodiesterase 9A (PDE9A))
    别名
    PDE9A (PDE9A 产品)
    别名
    PDE9A antibody, MGC116558 antibody, Pde9a antibody, HSPDE9A2 antibody, PDE9A1 antibody, phosphodiesterase 9A antibody, phosphodiesterase 9A S homeolog antibody, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A antibody, PDE9A antibody, pde9a.S antibody, Pde9a antibody, LOC100549810 antibody, pde9a antibody
    背景

    Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).

    Aliases: 5''-cyclic phosphodiesterase 9A antibody, cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody, FLJ90181 antibody, High affinity cGMP-specific 3'' antibody, High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody, HSPDE9A2 antibody, OTTHUMP00000109399 antibody, PDE 9A antibody, Pde9a antibody, PDE9A_HUMAN antibody, Phosphodiesterase 9A antibody, phosphodiesterase PDE9A21 antibody

    UniProt
    O76083
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