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PDE8A 抗体 (AA 596-829) (HRP)

PDE8A 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7155167
发货至: 中国
  • 抗原 See all PDE8A 抗体
    PDE8A (phosphodiesterase 8A (PDE8A))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 596-829
    适用
    • 41
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 37
    • 4
    克隆类型
    • 38
    • 3
    多克隆
    标记
    • 25
    • 5
    • 5
    • 2
    • 2
    • 2
    This PDE8A antibody is conjugated to HRP
    应用范围
    • 28
    • 24
    • 23
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3\',5\'-cyclic phosphodiesterase 8A protein (596-829AA)
    亚型
    IgG
    Top Product
    Discover our top product PDE8A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PDE8A (phosphodiesterase 8A (PDE8A))
    别名
    PDE8A (PDE8A 产品)
    背景

    Background: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 \'Ser-259\' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).

    Aliases: 5''-cyclic phosphodiesterase 8A antibody, cAMP specific cyclic nucleotide phosphodiesterase 8A antibody, FLJ16150 antibody, High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody, High affinity cAMP-specific and IBMX-insensitive 3'' antibody, HsT19550 antibody, PDE 8A antibody, PDE8A antibody, PDE8A_HUMAN antibody, Phosphodiesterase 8A antibody, Phosphodiesterase8A antibody, Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody

    UniProt
    O60658
    途径
    cAMP Metabolic Process
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