PDE8A 抗体 (AA 596-829)
-
- 抗原 See all PDE8A 抗体
- PDE8A (phosphodiesterase 8A (PDE8A))
-
抗原表位
- AA 596-829
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PDE8A antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3\',5\'-cyclic phosphodiesterase 8A protein (596-829AA)
- 亚型
- IgG
- Top Product
- Discover our top product PDE8A Primary Antibody
-
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- PDE8A (phosphodiesterase 8A (PDE8A))
- 别名
- PDE8A (PDE8A 产品)
- 别名
- PDE8A antibody, Pde8a antibody, HsT19550 antibody, AI551852 antibody, Pde8 antibody, RNPDE8A antibody, phosphodiesterase 8A antibody, PDE8A antibody, Pde8a antibody, pde8a antibody
- 背景
-
Background: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 \'Ser-259\' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).
Aliases: 5''-cyclic phosphodiesterase 8A antibody, cAMP specific cyclic nucleotide phosphodiesterase 8A antibody, FLJ16150 antibody, High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody, High affinity cAMP-specific and IBMX-insensitive 3'' antibody, HsT19550 antibody, PDE 8A antibody, PDE8A antibody, PDE8A_HUMAN antibody, Phosphodiesterase 8A antibody, Phosphodiesterase8A antibody, Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody
- UniProt
- O60658
- 途径
- cAMP Metabolic Process
-