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HNRNPD/AUF1 抗体 (AA 18-355)

HNRNPD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7155104
发货至: 中国
  • 抗原 See all HNRNPD/AUF1 (HNRNPD) 抗体
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    抗原表位
    • 11
    • 11
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    • 1
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    • 1
    • 1
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    AA 18-355
    适用
    • 61
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    宿主
    • 59
    • 2
    克隆类型
    • 60
    • 1
    多克隆
    标记
    • 39
    • 5
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    • 1
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    This HNRNPD/AUF1 antibody is un-conjugated
    应用范围
    • 49
    • 29
    • 28
    • 24
    • 6
    • 4
    • 2
    • 2
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Heterogeneous nuclear ribonucleoprotein D0 protein (18-355AA)
    亚型
    IgG
    Top Product
    Discover our top product HNRNPD Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
    别名
    HNRNPD (HNRNPD 产品)
    背景

    Background: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3\\\'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5\\\'-UUAG-3\\\' sequence and also weaker to the single-stranded 5\\\'-TTAGGG-3\\\' telomeric DNA repeat. Binds RNA oligonucleotides with 5\\\'-UUAGGG-3\\\' repeats more tightly than the telomeric single-stranded DNA 5\\\'-TTAGGG-3\\\' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

    Aliases: ARE binding protein AUFI type A antibody, AU-rich element RNA-binding protein 1 antibody, AUF antibody, AUF1 antibody, AUF1A antibody, Heterogeneous nuclear ribonucleoprotein D0 antibody, hnRNP D antibody, hnRNP D0 antibody, Hnrnpd antibody, hnRNPD0 antibody, HNRPD antibody, HNRPD_HUMAN antibody, P37 antibody

    UniProt
    Q14103
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