Hsc70 抗体 (AA 2-646)
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- 抗原 See all Hsc70 (HSPA8) 抗体
- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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抗原表位
- AA 2-646
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Hsc70 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein A purified
- 免疫原
- Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)
- 克隆位点
- 2G8F6
- 亚型
- IgG2b
- Top Product
- Discover our top product HSPA8 Primary Antibody
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- 应用备注
- Recommended dilution: WB: 1:10000-1:256000, IHC: 1:100-1:500, FC: 1:100-1:300, IP: 1 μL-4 μL,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
- 别名
- HSPA8 (HSPA8 产品)
- 别名
- hsc54 antibody, hsc70 antibody, hsc71 antibody, hsp71 antibody, hsp73 antibody, hspa10 antibody, lap1 antibody, nip71 antibody, HSC54 antibody, HSC70 antibody, HSC71 antibody, HSP71 antibody, HSP73 antibody, HSPA10 antibody, LAP1 antibody, NIP71 antibody, Hsc70 antibody, 2410008N15Rik antibody, Hsc71 antibody, Hsc73 antibody, Hsp73 antibody, Hspa10 antibody, wu:fb01g06 antibody, wu:fi48b06 antibody, heat shock protein family A (Hsp70) member 8 L homeolog antibody, heat shock protein family A (Hsp70) member 8 antibody, heat shock 70kDa protein 8 antibody, heat shock protein 8 antibody, hspa8.L antibody, HSPA8 antibody, Hspa8 antibody, hspa8 antibody
- 背景
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Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP
Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10
- UniProt
- P11142
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