HSPA1L 抗体 (AA 420-641)
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- 抗原 See all HSPA1L 抗体
- HSPA1L (Heat Shock 70kDa Protein 1-Like (HSPA1L))
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抗原表位
- AA 420-641
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSPA1L antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Heat shock 70 kDa protein 1-like protein (420-641AA)
- 亚型
- IgG
- Top Product
- Discover our top product HSPA1L Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HSPA1L (Heat Shock 70kDa Protein 1-Like (HSPA1L))
- 别名
- HSPA1L (HSPA1L 产品)
- 别名
- Hsc70t antibody, Msh5 antibody, HSPA1L antibody, hspa1l antibody, MGC147483 antibody, Hsp70-3 antibody, HSP70-1L antibody, HSP70-HOM antibody, HSP70T antibody, hum70t antibody, heat shock 70kDa protein 1-like antibody, heat shock protein 1-like antibody, heat shock 70 kDa protein 1-like antibody, heat shock protein family A (Hsp70) member 1 like antibody, HSPA1L antibody, Hspa1l antibody, LOC471967 antibody, hspa1l antibody, LOC474850 antibody, LOC102177850 antibody, LOC100050904 antibody
- 背景
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Background: Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365). Positive regulator of PRKN translocation to damaged mitochondria (PubMed:24270810).
Aliases: Heat shock 70 kDa protein 1 Hom antibody, Heat shock 70 kDa protein 1 like antibody, Heat shock 70 kDa protein 1-Hom antibody, Heat shock 70 kDa protein 1-like antibody, Heat shock 70 kDa protein 1L antibody, Heat shock 70kD protein like 1 antibody, HS71L_HUMAN antibody, HSP70 1L antibody, HSP70 HOM antibody, HSP70-Hom antibody, HSPA1L antibody, hum70t antibody, Spermatid specific heat shock protein 70 antibody
- UniProt
- P34931
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