DKC1 抗体 (AA 94-170)
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- 抗原 See all DKC1 抗体
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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抗原表位
- AA 94-170
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DKC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human H/ACA ribonucleoprotein complex subunit 4 protein (94-170AA)
- 亚型
- IgG
- Top Product
- Discover our top product DKC1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
- 别名
- DKC1 (DKC1 产品)
- 背景
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Background: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\\\'psi\\\') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Aliases: CBF5 antibody, CBF5 homolog antibody, Cbf5p homolog antibody, DKC 1 antibody, DKC antibody, Dkc1 antibody, DKC1_HUMAN antibody, DKCX antibody, Dyskeratosis congenita 1 antibody, Dyskeratosis congenita 1 dyskerin antibody, Dyskerin antibody, H/ACA ribonucleoprotein complex subunit 4 antibody, NAP 57 antibody, NAP57 antibody, NOLA 4 antibody, NOLA4 antibody, Nopp140 associated protein of 57 kDa antibody, Nopp140-associated protein of 57 kDa antibody, Nucleolar protein family A member 4 antibody, Nucleolar protein NAP57 antibody, snoRNP protein DKC1 antibody, XAP 101 antibody, XAP101 antibody
- UniProt
- O60832
- 途径
- Telomere Maintenance
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