GRB7 抗体 (AA 233-532)
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- 抗原 See all GRB7 抗体
- GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
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抗原表位
- AA 233-532
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRB7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)
- 亚型
- IgG
- Top Product
- Discover our top product GRB7 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
- 别名
- GRB7 (GRB7 产品)
- 别名
- GRB7 antibody, mKIAA4028 antibody, growth factor receptor bound protein 7 antibody, GRB7 antibody, Grb7 antibody
- 背景
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Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5\\\'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).
Aliases: B47 antibody, Epidermal growth factor receptor GRB 7 antibody, Epidermal growth factor receptor GRB-7 antibody, GRB7 adapter protein antibody, GRB7 antibody, GRB7_HUMAN antibody, Growth factor receptor bound protein 7 antibody, Growth factor receptor-bound protein 7 antibody, OTTHUMP00000164349 antibody, OTTHUMP00000164350 antibody, OTTHUMP00000164351 antibody, OTTHUMP00000164352 antibody
- UniProt
- Q14451
- 途径
- EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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