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GRB14 抗体 (AA 294-397)

GRB14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7154498
发货至: 中国
  • 抗原 See all GRB14 抗体
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    抗原表位
    • 15
    • 4
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    AA 294-397
    适用
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    宿主
    • 31
    克隆类型
    • 31
    多克隆
    标记
    • 13
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    This GRB14 antibody is un-conjugated
    应用范围
    • 13
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    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
    别名
    GRB14 (GRB14 产品)
    别名
    GRB14 antibody, AI505286 antibody, growth factor receptor bound protein 14 antibody, GRB14 antibody, grb14 antibody, Grb14 antibody
    背景

    Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

    Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody

    UniProt
    Q14449
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