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GRHL3 抗体 (AA 31-182)

GRHL3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7154380
发货至: 中国
  • 抗原 See all GRHL3 抗体
    GRHL3 (Grainyhead-Like 3 (GRHL3))
    抗原表位
    • 15
    • 9
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-182
    适用
    • 34
    • 10
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    宿主
    • 32
    • 2
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    This GRHL3 antibody is un-conjugated
    应用范围
    • 27
    • 20
    • 7
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Grainyhead-like protein 3 homolog protein (31-182AA)
    亚型
    IgG
    Top Product
    Discover our top product GRHL3 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GRHL3 (Grainyhead-Like 3 (GRHL3))
    别名
    GRHL3 (GRHL3 产品)
    别名
    GRHL3 antibody, SOM antibody, TFCP2L4 antibody, AI561912 antibody, Get1 antibody, Som antibody, Tfcp2l4 antibody, ct antibody, grainyhead like transcription factor 3 antibody, grainyhead-like 3 (Drosophila) antibody, grainyhead-like transcription factor 3 antibody, GRHL3 antibody, Grhl3 antibody
    背景

    Background: Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5\\\'-AACCGGTT-3\\\' acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation. Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (By similarity). Also required for proper development of the oral periderm (PubMed:24360809). No genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122).

    Aliases: Drosophila antibody, Grainyhead like 3 antibody, Grainyhead like protein 3 homolog antibody, Grainyhead-like protein 3 homolog antibody, grhl3 antibody, GRHL3_HUMAN antibody, Sister of mammalian grainyhead antibody, Sister of mammalian grainyhead protein antibody, SOM antibody, TFCP2L4 antibody, Transcription factor CP2 like 4 antibody, Transcription factor CP2-like 4 antibody

    UniProt
    Q8TE85
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