GANP 抗体 (AA 292-435)
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- 抗原 See all GANP (MCM3AP) 抗体
- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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抗原表位
- AA 292-435
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GANP antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Germinal-center associated nuclear protein (292-435AA)
- 亚型
- IgG
- Top Product
- Discover our top product MCM3AP Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
- 别名
- MCM3AP (MCM3AP 产品)
- 别名
- GANP antibody, MAP80 antibody, SAC3 antibody, mKIAA0572 antibody, minichromosome maintenance complex component 3 associated protein antibody, germinal-center associated nuclear protein antibody, Mcm3ap antibody, MCM3AP antibody, mcm3ap antibody, LOC100026233 antibody
- 背景
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Background: Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Aliases: 80 kDa MCM3 associated protein antibody, 80 kDa MCM3-associated protein antibody, FLJ44336 antibody, FLJ45306 antibody, Germinal center associated nuclear protein antibody, KIAA0572 antibody, MAP80 antibody, MCM3 import protein antibody, MCM3 minichromosome maintenance deficient 3 associated protein antibody, MCM3A antibody, MCM3A_HUMAN antibody, Mcm3ap antibody, Minichromosome maintenance complex component 3 associated protein antibody, Minichromosome maintenance deficient 3 associated protein antibody, Minichromosome maintenance protein 3 associated protein antibody, Protein GANP antibody, SAC3 antibody
- UniProt
- O60318
- 途径
- Protein targeting to Nucleus
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