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- 抗原 See all GEMIN8 抗体
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
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抗原表位
- AA 1-242
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GEMIN8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Gem-associated protein 8 protein (1-242AA)
- 亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) antibody
GEMIN8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) (C-Term) antibodyGEMIN8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
- 别名
- GEMIN8 (GEMIN8 产品)
- 别名
- FAM51A1 antibody, B130034M20Rik antibody, B930082C09Rik antibody, BC023488 antibody, gemin-8 antibody, gem nuclear organelle associated protein 8 antibody, gemin8 antibody, GEMIN8 antibody, Gemin8 antibody
- 背景
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Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Aliases: GEMIN8 antibody, FAM51A1Gem-associated protein 8 antibody, Gemin-8 antibody, Protein FAM51A1 antibody
- UniProt
- Q9NWZ8
- 途径
- Ribonucleoprotein Complex Subunit Organization
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