GEMIN4 抗体 (AA 741-848)
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- 抗原 See all GEMIN4 抗体
- GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
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抗原表位
- AA 741-848
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GEMIN4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Gem-associated protein 4 protein (741-848AA)
- 亚型
- IgG
- Top Product
- Discover our top product GEMIN4 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
- 别名
- GEMIN4 (GEMIN4 产品)
- 别名
- HC56 antibody, HCAP1 antibody, HHRF-1 antibody, p97 antibody, 4932415L08Rik antibody, AU015359 antibody, im:7143815 antibody, wu:fc41c09 antibody, zgc:110169 antibody, GEMIN4 antibody, RGD1563715 antibody, gem nuclear organelle associated protein 4 antibody, gem (nuclear organelle) associated protein 4 antibody, GEMIN4 antibody, Gemin4 antibody, gemin4 antibody
- 背景
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Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Aliases: GEMIN4 antibody, Gem-associated protein 4 antibody, Gemin-4 antibody, Component of gems 4 antibody, p97 antibody
- UniProt
- P57678
- 途径
- Ribonucleoprotein Complex Subunit Organization
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