WDR59 抗体 (AA 619-862) (Biotin)
Quick Overview for WDR59 抗体 (AA 619-862) (Biotin) (ABIN7153710)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 619-862
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- WDR59 (WD Repeat Domain 59 (WDR59))
-
别名
- WDR59
-
背景
-
Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
Aliases: WDR59 antibody, KIAA1923 antibody, FP977 antibody, GATOR complex protein WDR59 antibody, WD repeat-containing protein 59 antibody
-
UniProt
- Q6PJI9
抗原
-