WDR24 抗体 (AA 1-298) (Biotin)
-
- 抗原 See all WDR24 products
- WDR24 (WD Repeat Domain 24 (WDR24))
-
抗原表位
- AA 1-298
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This WDR24 antibody is conjugated to Biotin
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human GATOR complex protein WDR24 protein (1-298AA)
- 亚型
- IgG
-
anti-WD Repeat Domain 24 (WDR24) (AA 1-298) antibody
WDR24 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- WDR24 (WD Repeat Domain 24 (WDR24))
- 别名
- WDR24 (WDR24 产品)
- 别名
- C16orf21 antibody, JFP7 antibody, BC037651 antibody, wu:fd05f12 antibody, zgc:55946 antibody, WD repeat domain 24 antibody, WD repeat domain 24 L homeolog antibody, WDR24 antibody, Wdr24 antibody, wdr24 antibody, wdr24.L antibody
- 背景
-
Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody
- UniProt
- Q96S15
-
