Mare/Nprl3/C16orf35 抗体 (AA 349-482)
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- 抗原 See all Mare/Nprl3/C16orf35 (C16orf35) 抗体
- Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
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抗原表位
- AA 349-482
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Mare/Nprl3/C16orf35 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human GATOR complex protein NPRL3 protein (349-482AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
- 别名
- NPRL3 (C16orf35 产品)
- 别名
- C16orf35 antibody, CGTHBA antibody, HS-40 antibody, MARE antibody, NPR3 antibody, RMD11 antibody, Aag antibody, HS-26 antibody, Mare antibody, Phg antibody, Prox1 antibody, m(alpha)RE antibody, RGD1308665 antibody, c16orf35 antibody, cgthba antibody, hs-40 antibody, mare antibody, npr3 antibody, nprl3 antibody, rmd11 antibody, NPR3 like, GATOR1 complex subunit antibody, nitrogen permease regulator-like 3 antibody, NPR3-like, GATOR1 complex subunit antibody, NPR3-like, GATOR1 complex subunit L homeolog antibody, NPRL3 antibody, Nprl3 antibody, nprl3.L antibody
- 背景
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Background: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Aliases: otein antibody, Alpha-globin regulatory element-containing gene protein antibody, C16ORF35 antibody, CGTHBA antibody, Conserved gene telomeric to alpha globin cluster antibody, HS 40 antibody, MARE antibody, Nitrogen permease regulator 3-like protein antibody, Nitrogen permease regulator-like 3 (S. cerevisiae) antibody, NPR3 antibody, NPRL3 antibody, NPRL3_HUMAN antibody, Protein CGTHBA antibody, RMD11 antibody
- UniProt
- Q12980
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