MIOS 抗体 (AA 1-237) (FITC)
Quick Overview for MIOS 抗体 (AA 1-237) (FITC) (ABIN7153699)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-237
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human GATOR complex protein MIOS protein (1-237AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MIOS (WD Repeat-Containing Protein Mio (MIOS))
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别名
- MIOS
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背景
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
Aliases: MIOS antibody, GATOR complex protein MIOS antibody, Missing oocyte meiosis regulator homolog antibody
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UniProt
- Q9NXC5
抗原
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