Gasdermin A 抗体 (AA 64-172)
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- 抗原 See all Gasdermin A (GSDMA) 抗体
- Gasdermin A (GSDMA)
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抗原表位
- AA 64-172
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Gasdermin A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Gasdermin-A protein (64-172AA)
- 亚型
- IgG
- Top Product
- Discover our top product GSDMA Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Gasdermin A (GSDMA)
- 别名
- GSDMA (GSDMA 产品)
- 别名
- BB149167 antibody, Gsdm antibody, Gsdm1 antibody, Gsdma1 antibody, H312E antibody, GSDM1 antibody, GSDM antibody, gasdermin A antibody, Gsdma antibody, GSDMA antibody
- 背景
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Background: May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
Aliases: GSDMA antibody, GSDM antibody, GSDM1 antibody, FKSG9Gasdermin-A antibody, Gasdermin-1 antibody
- UniProt
- Q96QA5
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