GRK6 抗体 (AA 1-170)
-
- 抗原 See all GRK6 抗体
- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
-
抗原表位
- AA 1-170
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GRK6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human G protein-coupled receptor kinase 6 protein (1-170AA)
- 亚型
- IgG
- Top Product
- Discover our top product GRK6 Primary Antibody
-
-
- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
- 别名
- GRK6 (GRK6 产品)
- 别名
- MGC83187 antibody, GRK6 antibody, GPRK6 antibody, Gprk6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase 6 S homeolog antibody, GRK6 antibody, grk6.S antibody, grk6 antibody, Grk6 antibody
- 背景
-
Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Aliases: FLJ32135 antibody, G protein coupled receptor kinase 6 antibody, G protein coupled receptor kinase GRK6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase GRK6 antibody, Gprk6 antibody, Grk6 antibody, GRK6_HUMAN antibody
- UniProt
- P43250
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
-