FZD7 抗体 (AA 161-239)
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- 抗原 See all FZD7 抗体
- FZD7 (Frizzled Family Receptor 7 (FZD7))
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抗原表位
- AA 161-239
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Frizzled-7 protein (161-239AA)
- 亚型
- IgG
- Top Product
- Discover our top product FZD7 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- 别名
- FZD7 (FZD7 产品)
- 别名
- FzE3 antibody, Fz-7 antibody, Xfz7 antibody, frizzled-7 antibody, frizzled7 antibody, frz-7 antibody, frz7 antibody, fz7 antibody, fzd7-a antibody, fzd7-b antibody, fze3 antibody, Fz7 antibody, cFz-7 antibody, fb38g02 antibody, fc44b09 antibody, fz13 antibody, fz7a antibody, fz7b antibody, wu:fb38g02 antibody, wu:fc44b09 antibody, zg13 antibody, frizzled class receptor 7 antibody, frizzled class receptor 7 L homeolog antibody, frizzled class receptor 7b antibody, FZD7 antibody, fzd7.L antibody, fzd7 antibody, Fzd7 antibody, fzd7b antibody
- 背景
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Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Aliases: Frizzled 7, seven transmembrane spanning receptor antibody, frizzled class receptor 7 antibody, Frizzled drosophila homolog of 7 antibody, Frizzled family receptor 7 antibody, Frizzled homolog 7 antibody, Frizzled-7 antibody, Frizzled7 antibody, Fz 7 antibody, Fz-7 antibody, Fz7 antibody, FZD 7 antibody, FZD7 antibody, FZD7_HUMAN antibody, FzE 3 antibody, FzE3 antibody, hFz 7 antibody, hFz7 antibody, Homolog of Drosophila Frizzled 7 antibody, OTTHUMP00000163742 antibody
- UniProt
- O75084
- 途径
- WNT signaling, Stem Cell Maintenance
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