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- 抗原 See all FZD4 抗体
- FZD4 (Frizzled Family Receptor 4 (FZD4))
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抗原表位
- AA 37-222
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Frizzled-4 protein (37-222AA)
- 亚型
- IgG
- Top Product
- Discover our top product FZD4 Primary Antibody
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anti-Frizzled Family Receptor 4 (FZD4) (AA 37-222) antibody
FZD4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F3A7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (Middle Region) antibodyFZD4 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 11-60) antibodyFZD4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Atto 594)FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Atto 488)FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Atto 390)FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Atto 390
anti-Frizzled Family Receptor 4 (FZD4) (AA 107-206) antibodyFZD4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (FITC)FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Alkaline Phosphatase (AP))FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Frizzled Family Receptor 4 (FZD4) (AA 100-200) antibody (Biotin)FZD4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Biotin
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- 应用备注
- Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- 别名
- FZD4 (FZD4 产品)
- 别名
- CG4626 antibody, DFz4 antibody, Dfz4 antibody, Dm Fz4 antibody, Dmel\\CG4626 antibody, Fz4 antibody, anon-WO0170980.10 antibody, anon-WO0170980.11 antibody, fz1 antibody, zg01 antibody, CD344 antibody, EVR1 antibody, FEVR antibody, FZD4S antibody, Fz-4 antibody, FzE4 antibody, GPCR antibody, hFz4 antibody, frizzled4 antibody, fz4 antibody, FZ-4 antibody, frizzled 4 antibody, frizzled class receptor 4 antibody, frizzled-4 antibody, frizzled class receptor 4 S homeolog antibody, fz4 antibody, fzd4 antibody, Tsp_10376 antibody, FZD4 antibody, Fzd4 antibody, fzd4.S antibody
- 背景
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Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP). In retina, it can be both activated by Wnt protein-binding, but also by a Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accumulation and stimulation of LEF/TCF-mediated transcriptional programs. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Aliases: CD 344 antibody, CD 344 antigen antibody, CD344 antibody, CD344 antigen antibody, EVR1 antibody, FEVR antibody, Frizzled (Drosophila) homolog 4 antibody, Frizzled 4 antibody, Frizzled family receptor 4 antibody, Frizzled homolog 4 (Drosophila) antibody, Frizzled-4 antibody, Fz 4 antibody, Fz-4 antibody, Fz4 antibody, FZD4 antibody, FZD4_HUMAN antibody, FZD4S antibody, FzE4 antibody, GPCR antibody, hFz4 antibody, MGC34390 antibody, WNT receptor frizzled 4 antibody
- UniProt
- Q9ULV1
- 途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
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