FZD1 抗体 (AA 125-225)
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- 抗原 See all FZD1 (Fzd1) 抗体
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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抗原表位
- AA 125-225
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Frizzled-10 protein (125-225AA)
- 亚型
- IgG
- Top Product
- Discover our top product Fzd1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- 别名
- FZD1 (Fzd1 产品)
- 别名
- CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody
- 背景
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Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Aliases: CD 350 antibody, CD 350 antigen antibody, CD350 antibody, Frizzled (Drosophila) homolog 10 antibody, Frizzled-10 antibody, FZ 10 antibody, Fz-10 antibody, FZ10 antibody, FZD 10 antibody, FZD10 antibody, FZD10_HUMAN antibody, FzE 7 antibody, FzE7 antibody, hFz 10 antibody, hFz10 antibody
- UniProt
- Q9ULW2
- 途径
- WNT signaling, Asymmetric Protein Localization
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