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FZD1 抗体 (AA 73-322)

Fzd1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7153175
发货至: 中国
  • 抗原 See all FZD1 (Fzd1) 抗体
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    抗原表位
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-322
    适用
    • 37
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 5
    • 3
    • 1
    克隆类型
    • 38
    • 6
    多克隆
    标记
    • 28
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD1 antibody is un-conjugated
    应用范围
    • 28
    • 17
    • 11
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Frizzled-1 protein (73-322AA)
    亚型
    IgG
    Top Product
    Discover our top product Fzd1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    别名
    FZD1 (Fzd1 产品)
    背景

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

    Aliases: Chfz-1 antibody, Dfrizzled-1 antibody, DKFZp564G072 antibody, FLJ95923 antibody, Frizzled 1 antibody, Frizzled homolog 1 (Drosophila) antibody, Frizzled homolog 1 antibody, Frizzled-1 antibody, Fz receptor 1 antibody, Fz-1 antibody, Fz1 antibody, FZD1 antibody, FZD1_HUMAN antibody, FzE1 antibody, hFz1 antibody, Rfz1 antibody, Wnt receptor antibody, Xfrizzled-1 antibody

    UniProt
    Q9UP38
    途径
    WNT signaling, Asymmetric Protein Localization
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