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FZD1 抗体 (AA 73-322)

Fzd1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7153175
发货至: 中国
  • 抗原 See all FZD1 (Fzd1) 抗体
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    抗原表位
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-322
    适用
    • 37
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 5
    • 3
    • 1
    克隆类型
    • 38
    • 6
    多克隆
    标记
    • 28
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD1 antibody is un-conjugated
    应用范围
    • 28
    • 17
    • 11
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Frizzled-1 protein (73-322AA)
    亚型
    IgG
    Top Product
    Discover our top product Fzd1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    别名
    FZD1 (Fzd1 产品)
    别名
    CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody
    背景

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

    Aliases: Chfz-1 antibody, Dfrizzled-1 antibody, DKFZp564G072 antibody, FLJ95923 antibody, Frizzled 1 antibody, Frizzled homolog 1 (Drosophila) antibody, Frizzled homolog 1 antibody, Frizzled-1 antibody, Fz receptor 1 antibody, Fz-1 antibody, Fz1 antibody, FZD1 antibody, FZD1_HUMAN antibody, FzE1 antibody, hFz1 antibody, Rfz1 antibody, Wnt receptor antibody, Xfrizzled-1 antibody

    UniProt
    Q9UP38
    途径
    WNT signaling, Asymmetric Protein Localization
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