FOXN1 抗体 (AA 1-160) (Biotin)
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- 抗原 See all FOXN1 抗体
- FOXN1 (Forkhead Box N1 (FOXN1))
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抗原表位
- AA 1-160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXN1 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Forkhead box protein N1 protein (1-160AA)
- 亚型
- IgG
- Top Product
- Discover our top product FOXN1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FOXN1 (Forkhead Box N1 (FOXN1))
- 别名
- FOXN1 (FOXN1 产品)
- 别名
- nude antibody, whnb antibody, FOXN1 antibody, foxN1 antibody, foxN antibody, foxn1 antibody, FKHL20 antibody, RONU antibody, WHN antibody, D11Bhm185e antibody, Fkh19 antibody, HFH-11 antibody, Hfh11 antibody, Whn antibody, nu antibody, Rnu antibody, forkhead box N1 antibody, forkhead box protein N1 antibody, FOXN1 antibody, foxn1 antibody, foxN1 antibody, LOC100125524 antibody, Foxn1 antibody
- 背景
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Background: Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hematopoiesis and particularly T lineage progenitors within the bone marrow niche with age. Essential for the vascularization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively regulating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T-cell ontogeny (PubMed:21507891).
Aliases: FKHL20 antibody, Forkhead box N1 antibody, Forkhead box protein N1 antibody, FOXN 1 antibody, FOXN1 antibody, FOXN1_HUMAN antibody, RONU antibody, Rowett nude antibody, Transcription factor winged-helix nude antibody, WHN antibody, Winged helix nude antibody, Winged-helix transcription factor nude antibody
- UniProt
- O15353
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