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FCRL3 抗体 (AA 122-222) (Biotin)

FCRL3 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7152659
发货至: 中国
  • 抗原 See all FCRL3 抗体
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-222
    适用
    • 11
    • 1
    • 1
    宿主
    • 7
    • 4
    克隆类型
    • 7
    • 4
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    This FCRL3 antibody is conjugated to Biotin
    应用范围
    • 5
    • 4
    • 4
    • 3
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
    亚型
    IgG
    Top Product
    Discover our top product FCRL3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    别名
    FCRL3 (FCRL3 产品)
    别名
    CD307c antibody, FCRH3 antibody, IFGP3 antibody, IRTA3 antibody, SPAP2 antibody, fcrh3 antibody, ifgp3 antibody, irta3 antibody, spap2 antibody, xfl1.2 antibody, Fc receptor like 3 antibody, Fc receptor-like 3 L homeolog antibody, Fc receptor-like 3 antibody, Fc receptor-like 3 S homeolog antibody, FCRL3 antibody, fcrl3.L antibody, fcrl3 antibody, fcrl3.S antibody
    背景

    Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).

    Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody

    UniProt
    Q96P31
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