FCRL3 抗体 (AA 122-222)
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- 抗原 See all FCRL3 抗体
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
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抗原表位
- AA 122-222
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FCRL3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
- 亚型
- IgG
- Top Product
- Discover our top product FCRL3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
- 别名
- FCRL3 (FCRL3 产品)
- 别名
- CD307c antibody, FCRH3 antibody, IFGP3 antibody, IRTA3 antibody, SPAP2 antibody, fcrh3 antibody, ifgp3 antibody, irta3 antibody, spap2 antibody, xfl1.2 antibody, Fc receptor like 3 antibody, Fc receptor-like 3 L homeolog antibody, Fc receptor-like 3 antibody, Fc receptor-like 3 S homeolog antibody, FCRL3 antibody, fcrl3.L antibody, fcrl3 antibody, fcrl3.S antibody
- 背景
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Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).
Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody
- UniProt
- Q96P31
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