SUPT16H 抗体 (AA 187-282)
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- 抗原 See all SUPT16H 抗体
- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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抗原表位
- AA 187-282
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUPT16H antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human FACT complex subunit SPT16 protein (187-282AA)
- 亚型
- IgG
- Top Product
- Discover our top product SUPT16H Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
- 别名
- SUPT16H (SUPT16H 产品)
- 背景
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Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of \'Ser-392\' of p53/TP53 via its association with CK2 (casein kinase II).
Aliases: CDC68 antibody, Chromatin specific transcription elongation factor 140 kDa subunit antibody, Chromatin-specific transcription elongation factor 140 kDa subunit antibody, Facilitates chromatin transcription complex subunit SPT16 antibody, FACT 140 kDa subunit antibody, FACT antibody, FACT complex subunit SPT16 antibody, FACTp140 antibody, FLJ10857 antibody, FLJ14010 antibody, hSPT16 antibody, SP16H_HUMAN antibody, Suppressor of Ty 16 homolog antibody, Supt16h antibody
- UniProt
- Q9Y5B9
- 途径
- Chromatin Binding
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