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- 抗原 See all FBXO9 抗体
- FBXO9 (F-Box Protein 9 (FBXO9))
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抗原表位
- AA 13-111
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXO9 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human F-box only protein 9 protein (13-111AA)
- 亚型
- IgG
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anti-F-Box Protein 9 (FBXO9) (AA 338-447) antibody
FBXO9 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 1-437) antibodyFBXO9 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (Middle Region) antibodyFBXO9 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, Pig, 兔, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) antibodyFBXO9 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 179-228) antibodyFBXO9 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 马, Pig, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 431-447) antibodyFBXO9 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibodyFBXO9 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FBXO9 (F-Box Protein 9 (FBXO9))
- 别名
- FBXO9 (FBXO9 产品)
- 别名
- fbxo9 antibody, MGC75727 antibody, FBXO9 antibody, fbx9 antibody, FBX9 antibody, NY-REN-57 antibody, VCIA1 antibody, dJ341E18.2 antibody, wu:fc79g12 antibody, zgc:56212 antibody, zgc:77654 antibody, 9030401P18Rik antibody, AA986398 antibody, F-box protein 9 antibody, F-box only protein 9 antibody, f-box protein 9 antibody, F-box protein 9 L homeolog antibody, fbxo9 antibody, FBXO9 antibody, CpipJ_CPIJ012920 antibody, Tsp_03945 antibody, fbx9 antibody, Fbxo9 antibody, fbxo9.L antibody
- 背景
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
Aliases: Cross-immune reaction antigen 1 antibody, dJ341E18.2 antibody, DKFZp434C0118 antibody, F-box only protein 9 antibody, Fbp24 antibody, FBX09 antibody, FBX9 antibody, FBX9_HUMAN antibody, Fbxo9 antibody, KIAA0936 antibody, NY REN 57 antibody, OTTHUMP00000016628 antibody, OTTHUMP00000016629 antibody, OTTHUMP00000214588 antibody, Renal carcinoma antigen NY-REN-57 antibody, VCIA1 antibody
- UniProt
- Q9UK97
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