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EYA1 抗体 (AA 168-321) (HRP)

EYA1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7152358
发货至: 中国
  • 抗原 See all EYA1 抗体
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    抗原表位
    • 15
    • 15
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-321
    适用
    • 34
    • 24
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    宿主
    • 44
    • 1
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EYA1 antibody is conjugated to HRP
    应用范围
    • 27
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Eyes absent homolog 1 protein (168-321AA)
    亚型
    IgG
    Top Product
    Discover our top product EYA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    别名
    EYA1 (EYA1 产品)
    别名
    EYA1 antibody, bop antibody, bor antibody, XEya1 antibody, wu:fc13c10 antibody, zgc:100770 antibody, BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, EYA transcriptional coactivator and phosphatase 1 L homeolog antibody, EYA1 antibody, eya1 antibody, Eya1 antibody, eya1.L antibody
    背景

    Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19234442). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1, it plays an important role in hypaxial muscle development, in this it is functionally redundant with EYA2 (By similarity).

    Aliases: BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, Eya1 antibody, EYA1_HUMAN antibody, Eyes absent 1 antibody, Eyes absent 1 homolog antibody, Eyes absent homolog 1 (Drosophila) antibody, Eyes absent homolog 1 antibody, Eyes absent homolog1 antibody, MGC141875 antibody, OFC1 antibody

    UniProt
    Q99502
    途径
    Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
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