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EXOSC5 抗体 (AA 1-235)

EXOSC5 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7152293
发货至: 中国
  • 抗原 See all EXOSC5 抗体
    EXOSC5 (Exosome Component 5 (EXOSC5))
    抗原表位
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    AA 1-235
    适用
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 26
    • 5
    克隆类型
    • 28
    • 3
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC5 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 10
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Exosome complex component RRP46 protein (1-235AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EXOSC5 (Exosome Component 5 (EXOSC5))
    别名
    EXOSC5 (EXOSC5 产品)
    别名
    si:ch211-194n6.2 antibody, zgc:153707 antibody, EXOSC5 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody, hRrp46p antibody, p12B antibody, D7Wsu180e antibody, exosome component 5 antibody, exosc5 antibody, EXOSC5 antibody, Exosc5 antibody
    背景

    Background: Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

    Aliases: Chronic myelogenous leukemia tumor antigen 28 antibody, CML28 antibody, EXOS5_HUMAN antibody, EXOSC 5 antibody, Exosc5 antibody, Exosome complex component rrp46 antibody, exosome complex exonuclease RRP46 antibody, Exosome component 5 antibody, exosome component Rrp46 antibody, hRrp46p antibody, p12B antibody, Ribosomal RNA processing protein 46 antibody, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody, Ribosomal RNA-processing protein 46 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody

    UniProt
    Q9NQT4
    途径
    SARS-CoV-2 Protein Interactome
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