EIF3E 抗体 (AA 1-445)
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- 抗原 See all EIF3E 抗体
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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抗原表位
- AA 1-445
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3E antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Eukaryotic translation initiation factor 3 subunit E protein (1-445AA)
- 亚型
- IgG
- Top Product
- Discover our top product EIF3E Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
- 别名
- EIF3E (EIF3E 产品)
- 别名
- EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, 48kDa antibody, Eif3s6 antibody, Int6 antibody, eIF3-p48 antibody, eif3-p48 antibody, eif3s6 antibody, eif3s6-A antibody, eIF3e antibody, eIF3-S6 antibody, eif3s6-B antibody, EIF3SE antibody, eif3s6b antibody, im:7147439 antibody, QtsA-18056 antibody, eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E antibody, eukaryotic translation initiation factor 3 subunit E L homeolog antibody, eukaryotic translation initiation factor 3 subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E S homeolog antibody, eukaryotic translation initiation factor 3, subunit E, a antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E, b antibody, EIF3E antibody, Eif3e antibody, eif3e antibody, eif3e.L antibody, LOC692936 antibody, eif3e.S antibody, eif3ea antibody, eif-3.E antibody, eif3eb antibody, LOC108348260 antibody, int6 antibody
- 背景
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Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Aliases: eIF-3 p48 antibody, eIF3e antibody, EIF3E_HUMAN antibody, EIF3S6 antibody, eIFe antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit 6 (48kD) antibody, INT6 antibody, mammary tumor-associated protein INT6 antibody, murine mammary tumor integration site 6 (oncogene homolog) antibody, Viral integration site protein INT-6 homolog antibody
- UniProt
- P60228
- 途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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