EIF3A 抗体 (AA 1288-1379)
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- 抗原 See all EIF3A 抗体
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
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抗原表位
- AA 1288-1379
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Eukaryotic translation initiation factor 3 subunit A protein (1288-1379AA)
- 亚型
- IgG
- Top Product
- Discover our top product EIF3A Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
- 别名
- EIF3A (EIF3A 产品)
- 别名
- EIF3 antibody, EIF3S10 antibody, P167 antibody, TIF32 antibody, eIF3-p170 antibody, eIF3-theta antibody, p180 antibody, p185 antibody, EIF6 antibody, A830012B05Rik antibody, Csma antibody, Eif3 antibody, Eif3s10 antibody, mKIAA0139 antibody, ZH12 antibody, eif3s10 antibody, eIF3 p110 antibody, eIF3a antibody, eukaryotic translation initiation factor 3 subunit A antibody, eukaryotic translation initiation factor 3, subunit A antibody, eukaryotic translation initiation factor 3 subunit A S homeolog antibody, translation initiation factor eIF3a antibody, EIF3A antibody, Eif3a antibody, eif3a.S antibody, tif32 antibody
- 背景
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Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).
Aliases: centrosomin homolog antibody, cytoplasmic protein p167 antibody, eIF 3 theta antibody, eIF-3-theta antibody, EIF3 antibody, eIF3 p167 antibody, eIF3 p170 antibody, eIF3 p180 antibody, EIF3 p180 subunit antibody, eIF3 p185 antibody, eIF3 theta antibody, eIF3a antibody, EIF3A_HUMAN antibody, EIF3S10 antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit 10 antibody, eukaryotic translation initiation factor 3 subunit 10 theta 150 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit A antibody, OTTHUMP00000020589 antibody, P167 antibody, p180 antibody, p185 antibody, TIF32 antibody
- UniProt
- Q14152
- 途径
- Ribonucleoprotein Complex Subunit Organization
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