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EPH Receptor A5 抗体 (AA 246-514) (Biotin)

EPHA5 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7151844
发货至: 中国
  • 抗原 See all EPH Receptor A5 (EPHA5) 抗体
    EPH Receptor A5 (EPHA5)
    抗原表位
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 246-514
    适用
    • 42
    • 27
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 35
    • 10
    克隆类型
    • 35
    • 10
    多克隆
    标记
    • 26
    • 6
    • 4
    • 3
    • 3
    • 3
    This EPH Receptor A5 antibody is conjugated to Biotin
    应用范围
    • 41
    • 31
    • 21
    • 6
    • 3
    • 2
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)
    亚型
    IgG
    Top Product
    Discover our top product EPHA5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EPH Receptor A5 (EPHA5)
    别名
    EPHA5 (EPHA5 产品)
    背景

    Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

    Aliases: Brain-specific kinase antibody, bsk antibody, CEK 7 antibody, Eck like sequence 1 antibody, EHK 1 antibody, EHK-1 antibody, EK7 antibody, Els 1 antibody, EPH homology kinase 1 antibody, EPH-like kinase 7 antibody, EPHA5 antibody, EPHA5_HUMAN antibody, Ephrin type A receptor 5 antibody, Ephrin type-A receptor 5 antibody, HEK 7 antibody, hEK7 antibody, Receptor protein tyrosine kinase HEK 7 antibody, Rek 7 antibody, TYRO 4 antibody, Tyrosine protein kinase receptor EHK 1 antibody

    UniProt
    P54756
    途径
    RTK signaling
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