EPHA1 抗体 (AA 296-414) (Biotin)
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- 抗原 See all EPHA1 抗体
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
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抗原表位
- AA 296-414
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPHA1 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)
- 亚型
- IgG
- Top Product
- Discover our top product EPHA1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
- 别名
- EPHA1 (EPHA1 产品)
- 别名
- EPH antibody, EPHT antibody, EPHT1 antibody, 5730453L17Rik antibody, AL033318 antibody, Eph antibody, Esk antibody, EPHA9 antibody, EPH receptor A1 antibody, Eph receptor A1 antibody, EPHA1 antibody, Epha1 antibody
- 背景
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Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Aliases: EPH antibody, EPH receptor A1 antibody, EPH tyrosine kinase 1 antibody, EPH tyrosine kinase antibody, Epha1 antibody, EPHA1_HUMAN antibody, Ephrin receptor Eph A1 antibody, Ephrin type A receptor 1 antibody, Ephrin type-A receptor 1 antibody, EPHT 1 antibody, EPHT antibody, EPHT1 antibody, Erythropoietin producing hepatoma amplified sequence antibody, Erythropoietin-producing hepatoma receptor antibody, Esk antibody, hEpha1 antibody, MGC163163 antibody, Oncogene EPH antibody, Soluble EPHA1 variant 1 antibody, Soluble EPHA1 variant 2 antibody, Tyrosine protein kinase receptor EPH antibody, Tyrosine-protein kinase receptor EPH antibody
- UniProt
- P21709
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