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NGEF 抗体 (AA 495-710) (Biotin)

NGEF 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7151824
发货至: 中国
  • 抗原 See all NGEF 抗体
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    抗原表位
    • 15
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-710
    适用
    • 41
    • 41
    • 33
    • 3
    • 3
    • 3
    • 3
    宿主
    • 47
    • 1
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NGEF antibody is conjugated to Biotin
    应用范围
    • 39
    • 26
    • 26
    • 10
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Ephexin-1 protein (495-710AA)
    亚型
    IgG
    Top Product
    Discover our top product NGEF Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    别名
    NGEF (NGEF 产品)
    别名
    Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
    背景

    Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

    Aliases: ARHGEF27 antibody, Eph receptor-interacting exchange protein antibody, Eph-interacting exchange protein antibody, EPHEXIN antibody, Ephexin-1 antibody, Guanine nucleotide exchange factor, neuronal antibody, Neuronal guanine nucleotide exchange factor antibody, Ngef antibody, NGEF_HUMAN antibody

    UniProt
    Q8N5V2
    途径
    Neurotrophin Signaling Pathway
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