ERAP1 抗体 (AA 642-941)
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- 抗原 See all ERAP1 抗体
- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
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抗原表位
- AA 642-941
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ERAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Endoplasmic reticulum aminopeptidase 1 protein (642-941AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
- 别名
- ERAP1 (ERAP1 产品)
- 别名
- MGC166160 antibody, DKFZp469C044 antibody, ARTS-1 antibody, A-LAP antibody, ALAP antibody, APPILS antibody, ARTS1 antibody, ERAAP antibody, ERAAP1 antibody, PILS-AP antibody, PILSAP antibody, Arts1 antibody, PILSA antibody, Appils antibody, endoplasmic reticulum aminopeptidase 1 antibody, endoplasmic reticulum aminopeptidase 1b antibody, ERAP1 antibody, erap1 antibody, erap1b antibody, Erap1 antibody
- 背景
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Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
Aliases: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody
- UniProt
- Q9NZ08
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