SH3GLB1 抗体 (AA 1-365) (Biotin)
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- 抗原 See all SH3GLB1 抗体
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
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抗原表位
- AA 1-365
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SH3GLB1 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Endophilin-B1 protein (1-365AA)
- 亚型
- IgG
- Top Product
- Discover our top product SH3GLB1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
- 别名
- SH3GLB1 (SH3GLB1 产品)
- 别名
- im:5777505 antibody, wu:fa08f03 antibody, wu:fb13e12 antibody, MGC79086 antibody, sh3glb1 antibody, wu:fc55h11 antibody, wu:fj98d09 antibody, AA409932 antibody, AI314629 antibody, AU015566 antibody, Bif-1 antibody, mKIAA0491 antibody, PPP1R70 antibody, dJ612B15.2 antibody, SH3-domain GRB2-like endophilin B1b antibody, SH3 domain GRB2 like, endophilin B1 S homeolog antibody, SH3 domain GRB2 like, endophilin B1 antibody, SH3 domain containing GRB2 like, endophilin B1 antibody, SH3-domain GRB2-like endophilin B1a antibody, SH3-domain GRB2-like B1 (endophilin) antibody, SH3 domain -containing GRB2-like endophilin B1 antibody, SH3 domain containing GRB2 like endophilin B1 antibody, sh3glb1b antibody, sh3glb1.S antibody, sh3glb1 antibody, SH3GLB1 antibody, sh3glb1a antibody, Sh3glb1 antibody
- 背景
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Background: May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells, involved in maintenance of mitochondrial morphology and promotes neuronal viability.
Aliases: Bax interacting factor 1 antibody, Bax-interacting factor 1 antibody, Bif 1 antibody, Bif antibody, Bif-1 antibody, CGI 61 antibody, dJ612B15.2 antibody, Endophilin B1 antibody, Endophilin-B1 antibody, PPP1R70 antibody, Protein phosphatase 1 regulatory subunit 70 antibody, SH3 containing protein SH3GLB1 antibody, SH3 domain GRB2 like endophilin B1 antibody, SH3 domain-containing GRB2-like protein B1 antibody, Sh3glb1 antibody, SH3p13 antibody, SHLB1_HUMAN antibody
- UniProt
- Q9Y371
- 途径
- Autophagy
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