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SH3GLB1 抗体 (AA 1-365)

SH3GLB1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7151644
发货至: 中国
  • 抗原 See all SH3GLB1 抗体
    SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-365
    适用
    • 60
    • 11
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 56
    • 3
    • 1
    • 1
    克隆类型
    • 58
    • 3
    多克隆
    标记
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3GLB1 antibody is un-conjugated
    应用范围
    • 43
    • 26
    • 14
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Endophilin-B1 protein (1-365AA)
    亚型
    IgG
    Top Product
    Discover our top product SH3GLB1 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
    别名
    SH3GLB1 (SH3GLB1 产品)
    别名
    im:5777505 antibody, wu:fa08f03 antibody, wu:fb13e12 antibody, MGC79086 antibody, sh3glb1 antibody, wu:fc55h11 antibody, wu:fj98d09 antibody, AA409932 antibody, AI314629 antibody, AU015566 antibody, Bif-1 antibody, mKIAA0491 antibody, PPP1R70 antibody, dJ612B15.2 antibody, SH3-domain GRB2-like endophilin B1b antibody, SH3 domain GRB2 like, endophilin B1 S homeolog antibody, SH3 domain GRB2 like, endophilin B1 antibody, SH3 domain containing GRB2 like, endophilin B1 antibody, SH3-domain GRB2-like endophilin B1a antibody, SH3-domain GRB2-like B1 (endophilin) antibody, SH3 domain -containing GRB2-like endophilin B1 antibody, SH3 domain containing GRB2 like endophilin B1 antibody, sh3glb1b antibody, sh3glb1.S antibody, sh3glb1 antibody, SH3GLB1 antibody, sh3glb1a antibody, Sh3glb1 antibody
    背景

    Background: May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells, involved in maintenance of mitochondrial morphology and promotes neuronal viability.

    Aliases: Bax interacting factor 1 antibody, Bax-interacting factor 1 antibody, Bif 1 antibody, Bif antibody, Bif-1 antibody, CGI 61 antibody, dJ612B15.2 antibody, Endophilin B1 antibody, Endophilin-B1 antibody, PPP1R70 antibody, Protein phosphatase 1 regulatory subunit 70 antibody, SH3 containing protein SH3GLB1 antibody, SH3 domain GRB2 like endophilin B1 antibody, SH3 domain-containing GRB2-like protein B1 antibody, Sh3glb1 antibody, SH3p13 antibody, SHLB1_HUMAN antibody

    UniProt
    Q9Y371
    途径
    Autophagy
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