NEIL1 抗体 (AA 2-390) (HRP)
-
- 抗原 See all NEIL1 抗体
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
-
抗原表位
- AA 2-390
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NEIL1 antibody is conjugated to HRP
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Endonuclease 8-like 1 protein (2-390AA)
- 亚型
- IgG
- Top Product
- Discover our top product NEIL1 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
- 别名
- NEIL1 (NEIL1 产品)
- 别名
- FPG1 antibody, NEI1 antibody, hFPG1 antibody, 2810450N13Rik antibody, Nei1 antibody, nei-like DNA glycosylase 1 antibody, nei like DNA glycosylase 1 antibody, nei endonuclease VIII-like 1 (E. coli) antibody, Neil1 antibody, NEIL1 antibody
- 背景
-
Background: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3\'- and 5\'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Aliases: DNA (apurinic or apyrimidinic site) lyase Neil1 antibody, DNA glycosylase/AP lyase Neil 1 antibody, DNA glycosylase/AP lyase Neil1 antibody, DNA-(apurinic or apyrimidinic site) lyase Neil1 antibody, Endonuclease 8 like 1 antibody, Endonuclease 8-like 1 antibody, Endonuclease VIII antibody, Endonuclease VIII like 1 antibody, Endonuclease VIII-like 1 antibody, FLJ22402 antibody, FPG1 antibody, hFPG1 antibody, NEH 1 antibody, NEH1 antibody, NEI 1 antibody, Nei endonuclease VIII like 1 (E. coli) antibody, Nei endonuclease VIII like 1 antibody, Nei homolog 1 antibody, Nei like 1 antibody, Nei like protein 1 antibody, Nei-like protein 1 antibody, NEI1 antibody, NEIL 1 antibody, Neil1 antibody, NEIL1_HUMAN antibody
- UniProt
- Q96FI4
- 途径
- DNA Damage Repair
-