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- 抗原 See all NEIL1 抗体
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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抗原表位
- AA 2-390
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEIL1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Endonuclease 8-like 1 protein (2-390AA)
- 亚型
- IgG
- Top Product
- Discover our top product NEIL1 Primary Antibody
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anti-Endonuclease VIII-Like 1 (NEIL1) antibody
NEIL1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 43-314) antibodyNEIL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 187-476) antibodyNEIL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (C-Term) antibodyNEIL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) antibodyNEIL1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 1-390) antibodyNEIL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 1-390) antibodyNEIL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (C-Term) antibodyVerified NEIL1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
- 别名
- NEIL1 (NEIL1 产品)
- 别名
- FPG1 antibody, NEI1 antibody, hFPG1 antibody, 2810450N13Rik antibody, Nei1 antibody, nei-like DNA glycosylase 1 antibody, nei like DNA glycosylase 1 antibody, nei endonuclease VIII-like 1 (E. coli) antibody, Neil1 antibody, NEIL1 antibody
- 背景
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Background: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3\'- and 5\'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Aliases: DNA (apurinic or apyrimidinic site) lyase Neil1 antibody, DNA glycosylase/AP lyase Neil 1 antibody, DNA glycosylase/AP lyase Neil1 antibody, DNA-(apurinic or apyrimidinic site) lyase Neil1 antibody, Endonuclease 8 like 1 antibody, Endonuclease 8-like 1 antibody, Endonuclease VIII antibody, Endonuclease VIII like 1 antibody, Endonuclease VIII-like 1 antibody, FLJ22402 antibody, FPG1 antibody, hFPG1 antibody, NEH 1 antibody, NEH1 antibody, NEI 1 antibody, Nei endonuclease VIII like 1 (E. coli) antibody, Nei endonuclease VIII like 1 antibody, Nei homolog 1 antibody, Nei like 1 antibody, Nei like protein 1 antibody, Nei-like protein 1 antibody, NEI1 antibody, NEIL 1 antibody, Neil1 antibody, NEIL1_HUMAN antibody
- UniProt
- Q96FI4
- 途径
- DNA Damage Repair
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