ZNRF3 抗体 (AA 56-219)
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- 抗原 See all ZNRF3 抗体
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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抗原表位
- AA 56-219
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNRF3 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)
- 亚型
- IgG
- Top Product
- Discover our top product ZNRF3 Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
- 别名
- ZNRF3 (ZNRF3 产品)
- 别名
- BK747E2.3 antibody, RNF203 antibody, AA591877 antibody, BC019575 antibody, Gm1167 antibody, zinc and ring finger 3 antibody, Znrf3 antibody, ZNRF3 antibody
- 背景
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Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Aliases: ZNRF3 antibody, KIAA1133 antibody, RNF203 antibody, E3 ubiquitin-protein ligase ZNRF3 antibody, EC 2.3.2.27 antibody, RING finger protein 203 antibody, RING-type E3 ubiquitin transferase ZNRF3 antibody, Zinc/RING finger protein 3 antibody
- UniProt
- Q9ULT6
- 途径
- WNT signaling
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