UBR2 抗体 (AA 101-439) (HRP)
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- 抗原 See all UBR2 抗体
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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抗原表位
- AA 101-439
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBR2 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)
- 亚型
- IgG
- Top Product
- Discover our top product UBR2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- 别名
- UBR2 (UBR2 产品)
- 别名
- ba49a4.1 antibody, si:ch211-239i4.2 antibody, C6orf133 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, 9930021A08Rik antibody, AI462103 antibody, AW540746 antibody, E130209G04Rik antibody, mKIAA0349 antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antibody, UBR2 antibody, ubr2 antibody, ubr2.S antibody, Ubr2 antibody
- 背景
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Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Aliases: UBR2 antibody, C6orf133 antibody, KIAA0349 antibody, E3 ubiquitin-protein ligase UBR2 antibody, EC 2.3.2.27 antibody, N-recognin-2 antibody, RING-type E3 ubiquitin transferase UBR2 antibody, Ubiquitin-protein ligase E3-alpha-2 antibody, Ubiquitin-protein ligase E3-alpha-II antibody
- UniProt
- Q8IWV8
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