TRIM13 抗体 (AA 40-310)
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- 抗原 See all TRIM13 抗体
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
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抗原表位
- AA 40-310
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM13 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)
- 亚型
- IgG
- Top Product
- Discover our top product TRIM13 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
- 别名
- TRIM13 (TRIM13 产品)
- 别名
- TRIM13 antibody, RFP2 antibody, CAR antibody, DLEU5 antibody, LEU5 antibody, RNF77 antibody, 3110001L12Rik antibody, Rfp2 antibody, tripartite motif containing 13 antibody, ret finger protein 2 antibody, tripartite motif-containing 13 antibody, TRIM13 antibody, LOC100338599 antibody, Trim13 antibody
- 背景
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Background: E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.
Aliases: B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, CAR antibody, DLEU5 antibody, E3 ubiquitin-protein ligase TRIM13 antibody, HGNC:9976 antibody, LEU5 antibody, Leukemia associated protein 5 antibody, Leukemia-associated protein 5 antibody, Putative tumor suppressor RFP2 antibody, Ret finger protein 2 antibody, RFP2 antibody, RING finger protein 77 antibody, RNF77 antibody, TRI13_HUMAN antibody, Trim13 antibody, Tripartite motif protein 13 antibody, Tripartite motif-containing protein 13 antibody
- UniProt
- O60858
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