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TRIM11 抗体 (AA 267-468)

TRIM11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7151238
发货至: 中国
  • 抗原 See all TRIM11 抗体
    TRIM11 (Tripartite Motif Containing 11 (TRIM11))
    抗原表位
    • 9
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 267-468
    适用
    • 48
    • 20
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 2
    克隆类型
    • 48
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM11 antibody is un-conjugated
    应用范围
    • 38
    • 19
    • 17
    • 13
    • 6
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase TRIM11 protein (267-468AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TRIM11 (Tripartite Motif Containing 11 (TRIM11))
    别名
    TRIM11 (TRIM11 产品)
    别名
    BIA1 antibody, RNF92 antibody, TRIM11 antibody, tripartite motif containing 11 antibody, tripartite motif-containing 11 antibody, TRIM11 antibody, Trim11 antibody
    背景

    Background: E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.

    Aliases: BIA 1 antibody, BIA1 antibody, E3 ubiquitin protein ligase TRIM11 antibody, E3 ubiquitin-protein ligase TRIM11 antibody, Protein BIA1 antibody, RING finger protein 92 antibody, RING type E3 ubiquitin transferase TRIM11 antibody, RNF 92 antibody, RNF92 antibody, TRI11_HUMAN antibody, Trim 11 antibody, TRIM11 antibody, Tripartite motif containing 11 antibody, tripartite motif protein 11 antibody, Tripartite motif-containing protein 11 antibody

    UniProt
    Q96F44
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