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RNF31 抗体 (AA 421-700) (Biotin)

RNF31 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7151189
发货至: 中国
  • 抗原 See all RNF31 抗体
    RNF31 (Ring Finger Protein 31 (RNF31))
    抗原表位
    • 14
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 421-700
    适用
    • 46
    • 22
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 45
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF31 antibody is conjugated to Biotin
    应用范围
    • 41
    • 19
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase RNF31 protein (421-700AA)
    亚型
    IgG
    Top Product
    Discover our top product RNF31 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RNF31 (Ring Finger Protein 31 (RNF31))
    别名
    RNF31 (RNF31 产品)
    别名
    RNF31 antibody, HOIP antibody, ZIBRA antibody, AL033293 antibody, BC031509 antibody, Flj10111 antibody, Paul antibody, mFLJ00217 antibody, ring finger protein 31 antibody, RNF31 antibody, rnf31 antibody, Rnf31 antibody
    背景

    Background: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear (\\\'Met-1\\\'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.

    Aliases: E3 ubiquitin protein ligase RNF31 antibody, FLJ10111 antibody, FLJ23501 antibody, HOIL 1L interacting protein antibody, HOIL-1-interacting protein antibody, HOIL1L interacting protein antibody, HOIP antibody, RING finger protein 31 antibody, RNF31 antibody, RNF31_HUMAN antibody, ZIBRA antibody, Zinc in between ring finger ubiquitin associated domain antibody, Zinc in-between-RING-finger ubiquitin-associated domain protein antibody

    UniProt
    Q96EP0
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