RNF128 抗体 (AA 229-400) (HRP)
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- 抗原 See all RNF128 抗体
- RNF128 (Ring Finger Protein 128 (RNF128))
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抗原表位
- AA 229-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF128 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
- 亚型
- IgG
- Top Product
- Discover our top product RNF128 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RNF128 (Ring Finger Protein 128 (RNF128))
- 别名
- RNF128 (RNF128 产品)
- 别名
- rnf128 antibody, wu:fb57h05 antibody, zgc:77843 antibody, 1300002C13Rik antibody, AI987883 antibody, GRAIL antibody, Greul1 antibody, RGD1566282 antibody, grail antibody, greul1 antibody, ring finger protein 128a antibody, ring finger protein 128, E3 ubiquitin protein ligase antibody, ring finger protein 128 antibody, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antibody, rnf128a antibody, RNF128 antibody, Rnf128 antibody, rnf128.L antibody
- 背景
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Background: E3 ubiquitin-protein ligase that catalyzes \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \'Lys-48\' linkages and COR1A with \'Lys-63\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.
Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody
- UniProt
- Q8TEB7
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