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RNF128 抗体 (AA 229-400) (FITC)

RNF128 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7151140
发货至: 中国
  • 抗原 See all RNF128 抗体
    RNF128 (Ring Finger Protein 128 (RNF128))
    抗原表位
    • 7
    • 5
    • 4
    • 2
    • 1
    AA 229-400
    适用
    • 35
    • 21
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF128 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
    亚型
    IgG
    Top Product
    Discover our top product RNF128 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RNF128 (Ring Finger Protein 128 (RNF128))
    别名
    RNF128 (RNF128 产品)
    背景

    Background: E3 ubiquitin-protein ligase that catalyzes \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \'Lys-48\' linkages and COR1A with \'Lys-63\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

    Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

    UniProt
    Q8TEB7
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