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- 抗原 See all RBX1 抗体
- RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
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抗原表位
- AA 1-108
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase RBX1 protein (1-108AA)
- 亚型
- IgG
- Top Product
- Discover our top product RBX1 Primary Antibody
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anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 74-108), (C-Term) antibody
RBX1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB48352 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1859CT866-7-47 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (C-Term) antibodyRBX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-50) antibodyRBX1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 小鸡, 马 WB, IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-100) antibodyRBX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (Middle Region) antibodyRBX1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
- 别名
- RBX1 (RBX1 产品)
- 别名
- BA554C12.1 antibody, RNF75 antibody, ROC1 antibody, 1500002P15Rik antibody, AA517855 antibody, im:7137515 antibody, zgc:136444 antibody, RBX1 antibody, ATRBX1 antibody, F7C8.160 antibody, F7C8_160 antibody, HRT1 antibody, REGULATOR OF CULLINS-1 antibody, RING-BOX 1 antibody, RING-box 1 antibody, hop21 antibody, BEST:CK01110 antibody, CG16982 antibody, CK01110 antibody, Dmel\CG16982 antibody, EG:115C2.11 antibody, Rbx1 antibody, Rbx1/Roc antibody, Roc antibody, Roc1alpha antibody, anon-EST:Posey65 antibody, dRbx1 antibody, dRoc1 antibody, dRoc1a antibody, ring-box 1 antibody, ring-box 1, E3 ubiquitin protein ligase antibody, RING-box 1 antibody, RING-box protein 1 antibody, RING-box protein 1a antibody, Regulator of cullins 1a antibody, RBX1 antibody, Rbx1 antibody, rbx1 antibody, MGG_08844 antibody, LOC9308017 antibody, rbx-1 antibody, Roc1a antibody
- 背景
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Background: E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.
Aliases: BA554C12.1 antibody, E3 ubiquitin-protein ligase RBX1 antibody, FLJ60363 antibody, MGC13357 antibody, MGC1481 antibody, OTTHUMP00000028983 antibody, Protein ZYP antibody, Rbx 1 antibody, Rbx1 antibody, RBX1_HUMAN antibody, Regulator of cullins 1 antibody, Ring box 1 antibody, Ring box 1 E3 ubiquitin protein ligase antibody, RING box protein 1 antibody, RING finger protein 75 antibody, RING finger protein antibody, RING-box protein 1 antibody, Ringbox protein 1 antibody, RNF 75 antibody, RNF75 antibody, ROC 1 antibody, ROC1 antibody, ZYP protein antibody
- UniProt
- P62877
- 途径
- Cell Division Cycle, M Phase, SARS-CoV-2 Protein Interactome
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