RBBP6 抗体 (AA 51-97) (HRP)
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- 抗原 See all RBBP6 抗体
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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抗原表位
- AA 51-97
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBBP6 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase RBBP6 protein (51-97AA)
- 亚型
- IgG
- Top Product
- Discover our top product RBBP6 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
- 别名
- RBBP6 (RBBP6 产品)
- 别名
- MY038 antibody, P2P-R antibody, PACT antibody, RBQ-1 antibody, SNAMA antibody, 4933422O15Rik antibody, AI316869 antibody, BB233631 antibody, C030034J04Rik antibody, C77662 antibody, rbbp6 antibody, MGC75882 antibody, RBBP6 antibody, im:7158869 antibody, rbbp6l antibody, RB binding protein 6, ubiquitin ligase antibody, retinoblastoma binding protein 6, ubiquitin ligase antibody, retinoblastoma binding protein 6 antibody, RBBP6 antibody, Rbbp6 antibody, rbbp6 antibody
- 背景
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Background: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites (CFSs) in a ZBTB38- and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359).
Aliases: DKFZp686P0638 antibody, DKFZp761B2423 antibody, E3 ubiquitin-protein ligase RBBP6 antibody, MY038 antibody, P2P R antibody, P2PR antibody, p53 associated cellular protein of testis antibody, p53-associated cellular protein of testis antibody, p53-associated cellular protein, testis-derived antibody, PACT antibody, Proliferation potential related protein antibody, Proliferation potential-related protein antibody, Protein P2P R antibody, Protein P2P-R antibody, Protein P2PR antibody, Protein RBQ 1 antibody, Protein RBQ1 antibody, RB binding protein 6, ubiquitin ligase antibody, RB binding Q protein 1 antibody, RBBP 6 antibody, Rbbp6 antibody, RBBP6_HUMAN antibody, RBQ 1 antibody, RBQ-1 antibody, RBQ1 antibody, Retinoblastoma binding protein 6 isoform 3 antibody, Retinoblastoma binding Q protein 1 antibody, Retinoblastoma-binding protein 6 antibody, Retinoblastoma-binding Q protein 1 antibody, SNAMA antibody, SNAMA, Drosophila, homolog of antibody
- UniProt
- Q7Z6E9
- 途径
- Regulatory RNA Pathways
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