MYLIP 抗体 (AA 266-445)
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- 抗原 See all MYLIP 抗体
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
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抗原表位
- AA 266-445
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYLIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
- 亚型
- IgG
- Top Product
- Discover our top product MYLIP Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- 别名
- MYLIP (MYLIP 产品)
- 别名
- IDOL antibody, MIR antibody, 9430057C20Rik antibody, Mir antibody, mylip antibody, wu:fj36b03 antibody, zgc:55987 antibody, MYLIP antibody, mir antibody, zgc:153767 antibody, myosin regulatory light chain interacting protein antibody, myosin regulatory light chain interacting protein a antibody, myosin regulatory light chain interacting protein L homeolog antibody, myosin regulatory light chain interacting protein b antibody, MYLIP antibody, Mylip antibody, mylipa antibody, mylip.L antibody, mylip antibody, mylipb antibody
- 背景
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Aliases: BM-023 antibody, BZF1 antibody, E3 ubiquitin protein ligase MYLIP antibody, E3 ubiquitin-protein ligase MYLIP antibody, Idol antibody, Inducible degrader of the LDL-receptor antibody, Lipoprotein receptor antibody, MIR antibody, MYLIP antibody, MYLIP_HUMAN antibody, Myosin regulatory light chain interacting protein antibody, PP5242 antibody
- UniProt
- Q8WY64
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